PURPOSE
To present a case of advancing keratoconus treated with corneal collagen cross-linking (CXL) with ultraviolet A (UVA) light and riboflavin complicated with sterile infiltrates.
METHODS
The patient’s cornea was de-epithelialized and CXL was performed with application of riboflavin and exposure to UVA light (370 nm, 3 mW/cm2) for 30 minutes.
RESULTS
Early in the postoperative period, the patient presented with 11 deep stromal infiltrates of 1 to 2 mm with clear demarked edges in a circle near the limbus with some clear cornea. Corneal cultures were negative. Treatment consisted of antibiotic ofloxacin and tobramycin four times daily, and dexamethasone drops six times daily. After 2 months, scars remained evident.
CONCLUSIONS
This complication has not been reported previously and may be an individual hypersensitivity reaction to the riboflavin or UVA light in the anterior stroma. [J Refract Surg. 2010;26(8):609-611.]
ABOUT THE AUTHORS
From Aristotle University of Thessaloniki and A’ University Eye-Clinic, AHEPA Hospital, Thessaloniki, Greece (Mangioris, Papadopoulou, Balidis, Poulas, Papadopoulos); and Institut für Refraktive und Ophthalmo-Chirurgie (IROC), Zurich, Switzerland (Seiler).
The authors have no financial interest in the materials presented herein.
This paper was presented at the 3rd International Congress of Corneal Cross Linking; December 8-10, 2007; Zurich, Switzerland.
Correspondence: Nikolaos Th. Papadopoulos, MD, A’ University Eye-Clinic, AHEPA Hospital, 1 Stilp Kiriakidis St, 54636 Thessaloniki, Greece. Tel: 30 2310 994 744; Fax: 30 2310 994 759; E-mail: papado@med.auth.gr
Received: December 25, 2008; Accepted: March 23, 2010
Posted online: April 15, 2010
doi:10.3928/1081597X-20100326-01
