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Table of Contents
Reliability of the IOLMaster in Measuring Corneal Power Changes After Hyperopic Photorefractive Keratectomy
Nicola Rosa, MD; Maddalena De Bernardo, MD; Maria Borrelli, MD; Maria Luisa Filosa, MD; Emma Minutillo, MD; Michele Lanza, MD Submitted: 12/9/08; Accepted: 6/22/10; Posted: 7/15/10
In a prospective series of 45 eyes treated consecutively with PRK using a SCHWIND ESIRIS excimer laser, an IOLMaster measurement of the change in corneal curvature did not correlate well with the refractive change, or with the equivalent K readings from the Holladay Report in the Pentacam, requiring a corrective regression formula for the IOLMaster readings.
doi:10.3928/1081597X-20100707-01 [Get full text]
Optical Quality in Eyes Implanted With Aspheric and Spherical Intraocular Lenses Assessed by NIDEK OPD-Scan: A Randomized, Bilateral, Clinical Trial
Marcony R. Santhiago, MD; Marcelo V. Netto, MD, PhD; Jackson Barreto, Jr, MD; Beatriz A.F. Gomes, MD; Cristiane D. Oliveira, MD; Newton Kara-Junior, MD, PhD Submitted: 6/30/09; Accepted: 6/17/10; Posted: 7/15/10
In a series of 25 patients, implanted in one eye with an aspheric Akreos AO IOL and in the other eye with a spherical Akreos Fit IOL, the refractive outcome was similar in both eyes, but the quality of vision as measured by the Strehl ratio, higher order RMS aberrations, and amount of spherical aberration with the NIDEK OPD-Scan aberrometer, were better with the aspheric IOL. A useful review of the literature is presented.
doi:10.3928/1081597X-20100714-01 [Get full text]
Refractive Stability of LASIK With the VISX 20/20 Excimer Laser vs ZB5M Phakic IOL Implantation in Patients With High Myopia (>-10.00 D): A 10-year Retrospective Study
Mohamad Rosman, MD, FRCSEd, FAMS; Jorge L. Alió, MD, PhD; Dolores Ortiz, PhD; Juan J. Pérez-Santonja, MD Submitted: 5/15/08; Accepted: 6/17/10; Posted: 7/15/10
In a retrospective series of eyes with myopia from approximately -10.00 to -20.00 D, 126 were treated with LASIK and 52 with the ZB5M anterior chamber phakic IOL. The mean myopic regression from 3 months to 10 years was -1.86 D for LASIK and -0.19 D for the PIOL.
doi:10.3928/1081597X-20100707-02 [Get full text]
Prospective, Contralateral Comparison of 120-μm and 90-μm LASIK Flaps Using the IntraLase FS60 Femtosecond Laser
Majid Moshirfar, MD; Bryndon B. Hatch, BA; JoAnn C. Chang, MD; Christopher J. Kurz, MD; Marcela F. Eugarrios, MD; Mark D. Mifflin, MD Submitted: 11/4/09; Accepted 5/28/10; Posted: 7/1/10
Thin-flap LASIK (intended flap thickness of 90- or 120-μm) was performed in a series of 94 eyes, resulting in visual acuity of 20/20 in 98% of eyes with 120-μm flaps and 95% of eyes with 90-μm flaps 6 months postoperatively, with all patients reporting increased quality of life postoperatively. No significant differences were found regarding contrast sensitivity, corrected distance visual acuity, total higher order aberrations, or patient-reported outcomes.
doi:10.3928/1081597X-20100624-01 [Get full text]
Corneal Density With the Pentacam After Photorefractive Keratectomy
Agnes I. Takacs, MD; Kata Mihaltz, MD; Zoltan Z. Nagy, MD, DSc Submitted: 10/19/09; Accepted: 5/28/10; Posted: 7/1/10
Using the Pentacam Scheimpflug system, corneal density was measured and corneal haze evaluated in unoperated eyes and eyes after myopic or hyperopic PRK, demonstrating its use for the detection and measurement of mild and moderate corneal opacities.
doi:10.3928/1081597X-20100618-02 [Get full text]
Posterior Corneal Elevation After LASIK With Three Flap Techniques as Measured by Pentacam
Dilraj S. Grewal, MD; Gagandeep S. Brar, MD; Satinder Pal Singh Grewal, MD Submitted: 12/10/09; Accepted: 5/11/10; Posted: 7/1/10
In a series of 90 eyes undergoing LASIK with a femtosecond or mechanical microkeratome flap or LASEK, the change in posterior corneal elevation 18 months after surgery was a clinically insignificant mean of approximately 6 μm in all three groups as measured by the Pentacam.
doi:10.3928/1081597X-20100618-01 [Get full text]
Wavefront-guided Photorefractive Keratectomy With the VISX Platform for Myopia
Simon R. Bababeygy, MD; Edward E. Manche, MD Submitted: 12/4/09; Accepted: 4/30/10; Posted: 6/15/10
In a retrospective study of 174 myopic eyes (MRSE range: –0.125 to –10.50 D) treated with wavefront-guided PRK using the VISX CustomVue S4 IR laser and followed for 12 months, 82% of eyes were within ±0.50 D of intended correction. UDVA was 20/20 or better in 94% of low to moderate myopic eyes and 76% in higher myopic eyes. There was minimal increase in higher order aberrations in lower myopes and an approximate doubling of total higher order aberrations in higher myopes.
doi:10.3928/1081597X-20100527-01 [Get full text]
Laboratory Measurement of the Absorption Coefficient of Riboflavin for Ultraviolet Light (365 nm)
Hans Peter Iseli, MD; Max Popp; Theo Seiler, MD, PhD; Eberhard Spoerl, PhD; Michael Mrochen, PhD Submitted: 2/15/10; Accepted: 4/21/10; Posted: 6/15/10
In a laboratory setting using different concentrations of riboflavin in a container irradiated by 365-nm ultraviolet light, a linear correlation exists between the absorption coefficient and riboflavin concentration, indicating that riboflavin concentration can be varied as a treatment parameter in corneal collagen cross-linking.
doi:10.3928/1081597X-20100604-01 [Get full text]
Correction of Astigmatism During Cataract Surgery: Toric Intraocular Lens Compared to Peripheral Corneal Relaxing Incisions
Jed T. Poll, MD; Li Wang, MD, PhD; Douglas D. Koch, MD; Mitchell P. Weikert, MD Submitted: 4/13/09; Accepted: 4/16/10; Posted: 6/15/10
In a series of eyes undergoing phacoemulsification for cataract, with preoperative keratometric astigmatism ranging from approximately 1.00 to 4.00 D, 77 eyes received a toric AcrySof IOL and 115 received 600-μm-deep peripheral limbal relaxing incisions. Mean postoperative astigmatism was 0.42 D in the toric group and 0.46 D in the incision group, with no statistically significant difference between the two groups, although eyes with astigmatism >2.26 D had better outcomes with the toric IOL.
doi:10.3928/1081597X-20100526-01[Get full text]
Unintended Epithelium-only Flap Creation Using a Femtosecond Laser During LASIK
George D. Kymionis, MD, PhD; Dimitra M. Portaliou, MD; Maria S. Krasia, MD; Alexandra E. Karavitaki, MD; Michael A. Grentzelos, MD; Sophia I. Panagopoulou, PhD; George A. Kounis, PhD; Ioannis G. Pallikaris, MD, PhD Submitted: 1/10/10; Accepted: 5/5/10; Posted: 6/1/10
The authors present a case of unintended epithelial flap creation during myopic femtosecond LASIK, demonstrating a possible complication of femtosecond laser use. [Get full text]
Initial Resident Refractive Surgical Experience: Outcomes of PRK and LASIK for Myopia
Michael D. Wagoner, MD, PhD; Joseph C. Wickard, MD; George R. Wandling, Jr, MD; Lisa C. Milder; Matthew P. Rauen, MD; Anna S. Kitzmann, MD; John E. Sutphin, MD; Kenneth M. Goins, MD Submitted: 11/8/09; Accepted: 5/5/10; Posted: 6/1/10
In a retrospective review of 153 cases of PRK or LASIK by 20 different residents using the VISX Star S4 platform, a UDVA of 20/20 or better was achieved in 95% of PRK eyes and 78% of LASIK eyes. One eye lost 2 lines of CDVA after LASIK. [Get full text]
Successful Treatment of Recurrent Epithelial Ingrowth Associated With Interface Fluid Syndrome, Flap Necrosis, and Epithelial Defects Following LASIK
Saba J. Elderkin, MD; Randy J. Epstein, MD; Dianna L. Seldomridge, MD, MBA Submitted: 6/30/09; Accepted: 4/27/10; Posted: 6/1/10
Two patients who developed flap necrosis preceded by recurrent epithelial ingrowth and interface fluid syndrome after LASIK were successfully treated with debridement and flap suturing and fibrin tissue adhesive application. [Get full text]
Is Excimer Laser Corneal Surgery Appropriate After Resolution of Corneal Edema in Fuchs Dystrophy by Descemet Membrane Endothelial Keratoplasty?
Francis W. Price, Jr, MD; Marianne O. Price, PhD; Frederico Guerra, MD Submitted: 10/9/09; Accepted: 4/21/10; Posted: 6/1/10
The authors seek to determine the safety of LASIK or PRK correction of the residual refractive error in a pseudophakic patient with Fuchs dystrophy who underwent Descemet membrane endothelial keratoplasty. [Get full text]
Refractive Outcome of Keratoconus Treated by Combined Femtosecond Laser and Big-bubble Deep Anterior Lamellar Keratoplasty
Luca Buzzonetti, MD; Antonio Laborante, MD; Gianni Petrocelli, MD Submitted: 8/27/09; Accepted: 4/21/10; Posted: 6/1/10
In a series of 13 eyes with keratoconus, recipient and donor corneal transplant lenticules were prepared in a mushroom-shape with a femtosecond laser, with residual host corneal stroma being removed manually with the big-bubble technique down to Descemet membrane. One year after surgery, the mean values for refractive sphere were -1.50 D and refractive astigmatism 2.00 D. [Get full text]
Bilateral Explantation of Visian Implantable Collamer Lenses Secondary to Bilateral Acute Angle Closure Resulting From a Non-pupillary Block Mechanism
Yousuf M. Khalifa, MD; Jason Goldsmith, MD; Majid Moshirfar, MD Submitted: 2/24/10; Accepted: 4/21/10; Posted: 6/1/10
The authors present the first published case of simultaneous, bilateral phakic posterior chamber IOL-induced non-pupillary block angle closure in a patient who underwent Visian ICL implantation. Anterior segment optical coherence tomography revealed profound vaulting of the ICL. [Get full text]
The Refractive Status and Vision Profile: Rasch Analysis of Subscale Validity
Vijaya K. Gothwal, PhD; Thomas A. Wright, BPsych(Hons); David B. Elliott, PhD; Konrad Pesudovs, PhD Submitted: 4/15/09; Accepted: 4/21/10; Posted: 5/17/10
The authors examined the performance of the subscales of the Refractive Status and Vision Profile (RSVP) questionnaire and found that none of the subscales fulfill all the requirements of the Rasch model. Therefore, investigators should abandon the use of the subscales and use the RSVP as a single questionnaire. [Get full text]
Dark-adapted Pupil Diameter as a Function of Age Measured With the NeurOptics Pupillometer
Jay C. Bradley, MD; Karl C. Bentley, MD; Aleem I. Mughal, MD; Hari Bodhireddy, BS; Sandra M. Brown, MD Submitted: 12/16/09; Accepted: 4/21/10; Posted: 5/17/10
In a series of 263 individuals aged 18 to 80 years, mean dark-adapted pupil diameter ranged from approximately 7 mm in the third decade to 5 mm in the eighth decade, findings consistent with 8 other published studies. [Get full text]
Correction of Residual Refractive Error in Pseudophakic Eyes With the Use of a Secondary Piggyback Toric Implantable Collamer Lens
Takashi Kojima, MD; Rie Horai; Shuya Hara, MD; Hideki Nakamura, MD; Tomoaki Nakamura, MD; Yuya Satoh, MD, PhD; Kazuo Ichikawa, MD, PhD Submitted: 12/3/09; Accepted: 4/16/10; Posted: 5/17/10
Eight pseudophakic eyes received piggyback toric ICLs to correct residual refractive error, with 62.5% of eyes within ±0.50 D and 87.5% of eyes within ±1.00 D of attempted refraction. [Get full text]
Effect of the Direct Application of Riboflavin and UVA on the Visian Implantable Collamer Lens
Farhad Hafezi, MD, PhD; Francois Majo, MD, PhD; Alaa M. El Danasoury, MD, FRCS Received: 10/16/09; Accepted: 4/8/10; Posted: 5/3/10
In vitro analysis of nine Visian ICLs that were subjected to corneal collagen cross-linking with riboflavin and ultraviolet A light with maximal and 10x the maximal dose of irradiation demonstrated no affects on the optical and material characteristics of the lenses. [Get full text]
Corneal Ectasia After LASIK Despite Low Preoperative Risk: Tomographic and Biomechanical Findings in the Unoperated, Stable, Fellow Eye
Renato Ambrósio, Jr, MD, PhD; Daniel G. Dawson, MD; Marcella Salomão, MD; Frederico P. Guerra, MD; Ana Laura C. Caiado, MD; Michael W. Belin, MD Received: 9/20/09; Accepted: 4/8/10; Posted: 5/3/10
Progressive ectasia after LASIK occurred despite a low risk score based on the Randleman Ectasia Risk Score System. The tomographic and biomechanical findings on the contralateral non-ectatic eye suggest these tests may enhance the sensitivity for screening ectasia susceptibility among refractive candidates. [Get full text]
Reproducibility of LASIK Flap Thickness Using the Zeiss Femtosecond Laser Measured Postoperatively by Optical Coherence Tomography
Won-Kyung Ju, MD; Jeong-Hye Lee, MD; Tae-Young Chung, MD, PhD; Eui-Sang Chung, MD, PhD Received: 9/9/09; Accepted: 4/8/10; Posted: 5/3/10
In a series of 87 myopic eyes undergoing LASIK, the flap was created by the Zeiss femtosecond laser and its thickness measured postoperatively by optical coherence tomography, demonstrating that the intended flap thickness and the achieved flap thickness were nearly identical and that the flap had a uniform thickness from edge to edge. [Get full text]
Aspheric Optical Zones: The Effective Optical Zone With the SCHWIND AMARIS
Massimo Camellin, MD; Samuel Arba Mosquera, MSc Received: 7/20/09; Accepted: 4/8/10; Posted: 5/3/10
In a retrospective series of 20 myopic eyes that underwent LASEK/epi-LASEK with the SCHWIND AMARIS platform with topography and aberrometry by the Keraton Scout, the effective optical zone as measured by corneal optical aberrations was approximately 0.25 mm smaller than the planned optical zone from 5.5 to 6.5 mm, and was the same size for 7.0- and 7.5-mm planned zones. [Get full text]
Ocular Response Analyzer Measurements in Keratoconus With Normal Central Corneal Thickness Compared With Matched Normal Control Eyes
Bruno M. Fontes, MD; Renato Ambrósio, Jr, MD, PhD; Guillermo Coca Velarde, DsC; Walton Nosé, MD Received: 11/12/09; Accepted: 4/7/10; Posted: 5/3/10
In a series of 19 eyes with keratoconus and 19 normal paired eyes, the corneal hysteresis and corneal resistance factor as measured by the Ocular Response Analyzer were insufficient to distinguish between the two groups, although both variables were statistically lower in the keratoconus eyes. [Get full text]
Higher Order Aberrations and Low Contrast Vision Function in Myopic Eyes (–3.00 to –6.00 D) Under Mesopic Conditions
Yan Wang, MD; Kanxing Zhao, MD, PhD; Xiaoyan Yang, MD; Jicang He, PhD; Wei Wang, PhD Received: 2/17/09; Accepted 4/7/10; Posted: 5/3/10
In a series of 52 normal myopic eyes in patients 18 to 35 years old, both spherical-like aberration (S4) and spherical aberration (C ) significantly reduced visual acuity at low contrast sensitivity levels, suggesting that less spherical aberration might improve visual function under mesopic conditions. [Get full text]
Surface Ablation With Iris Recognition and Dynamic Rotational Eye Tracking-based Tissue Saving Treatment With the Technolas 217z Excimer Laser
Gaurav Prakash, MD; Amar Agarwal, MS, FRCS, FRCOphth; Dhivya Ashok Kumar, MD; Soosan Jacob, MS, FRCS, DNB; Athiya Agarwal, MD, DO; Amrita Maity, BOptom Received: 8/6/09; Accepted: 3/30/10; Posted: 5/3/10
In a series of 122 myopic eyes treated with the Technolas 217z excimer laser using tissue-saving algorithms and iris recognition and rotational eye tracking, at 6 months, 94% of eyes with a spherical equivalent refraction within 0.05 D of intended and a tissue savings of approximately 5 to 30 μm compared to standard algorithms. [Get full text]
Corneal Infiltrates After Corneal Collagen Cross-linking
George F. Mangioris, MD; Domniki N. Papadopoulou, MD; Miltiadis O. Balidis, MD; Jordan L. Poulas, MD; Nikolaos Th. Papadopoulos, MD; Theo Sieler, MD Submitted: 12/2/08; Accepted: 3/23/10; Posted: 4/15/10
Sterile infiltrates after corneal collagen cross-linking with riboflavin and UVA light are reported. [Get full text]
Comparison of Optical Performance in Eyes Implanted With Aspheric Foldable, Spherical Foldable, and Rigid PMMA IOLs
Kim W. van Gaalen, PhD; Nomdo M. Jansonius, MD, PhD; Steven A. Koopmans, MD, PhD; Aart C. Kooijman, PhD Received: 7/30/09; Accepted: 3/9/10; Posted: 4/15/10
In a series of 52 eyes implanted with different styles of PMMA, aspheric foldable, and spherical foldable IOLs, there was no difference in postoperative visual acuity, contrast sensitivity, or higher order aberrations or root-mean-square of higher order aberrations. However, the eyes with aspheric IOLs had less spherical aberration and a smaller myopic shift. [Get full text]
Higher Order Aberrations Using the NIDEK OPD-Scan and AMO WaveScan
Colm McAlinden, BSc (Hons), MSc, MCOptom; Jonathan E. Moore, PhD, FRCOphth Submitted: 10/9/09; Accepted: 3/4/10; Posted: 4/15/10
Third to sixth order higher order aberrations were measured in 1072 eyes using the OPD-Scan and WaveScan. Medium consistency was found for coma and spherical aberration; poor consistency was found for all other aberrations and total root-mean-square of higher order aberrations. [Get full text]
Combined Kerarings and Artisan/Artiflex IOLs in Keratectasia
Hanefi Cakir, MD; Canan Asli Utine, MD, MSc Submitted: 11/7/09; Accepted: 3/2/10; Posted: 4/15/10
In a series of 10 eyes with various types of corneal ectasia, the sequential implantation of intracorneal Keraring segments followed by Artisan/Artiflex iris-fixated phakic intraocular lenses, produced considerable improvement in both refractive and visual acuity results in all eyes. [Get full text]
Comparison of the Toric Implantable Collamer Lens and Bioptics for Myopic Astigmatism
Sung-Ho Choi, MD; Myoung-Ok Lee, MD; Eui-Sang Chung, MD, PhD; Tae-Young Chung, MD, PhD Submitted: 7/21/09; Accepted: 3/2/10; Posted: 4/15/10
In a retrospective series of eyes with high compound myopic astigmatism, 20 eyes were treated with a phakic toric Implantable Collamer Lens (ICL) and 17 eyes with a spherical ICL followed by excimer laser surface ablation for residual astigmatism. The refractive and visual acuity outcomes at 1 year or greater were similar in the two groups. [Get full text]
Comparison of LASEK and LASIK With Thin and Ultrathin Flaps After Excimer Laser Ablation With the SCHWIND Aspheric Ablation Profile
Maria Clara Arbelaez, MD; Camila Vidal, OD; Samuel Arba Mosquera, MSc Submitted: 1/9/09; Accepted: 2/18/10; Posted: 4/15/10
In a retrospective study of LASEK, LASIK with a 130-µm microkeratome head, and LASIK with a 110-µm microkeratome head (approximately 30 eyes in each group) using the SCHWIND platform, there was general preservation of preoperative higher order aberrations and the overall outcomes of the surface ablation were similar to those of the thicker and thinner flap type ablations. [Get full text]
Evaluation of the Calhoun Vision UV Light Adjustable Lens Implanted Following Cataract Removal
Fritz H. Hengerer, MD; Ina Conrad-Hengerer, MD; Sabine E. Buchner, MSc; H. Burkhard Dick, MD Submitted: 11/8/09; Accepted: 2/16/10; Posted: 4/15/10
In a prospective clinical study, the Calhoun Vision Light Adjustable Lens was implanted at the end of cataract removal, and the power adjusted with one or two UV irradiation treatments followed by a final treatment that stabilized the refractive outcome. At 4 months after the stabilization lock-in procedure, the spherical equivalent refraction was ±0.25 D in 60%, ±0.50 D in 88%, and ±1.00 D in 100% of eyes, based upon the intended outcome. [Get full text]
Refractive Surgical Correction of Presbyopia With the AcuFocus Small Aperture Corneal Inlay: Two-year Follow-up
Orang Seyeddain, MD; Wolfgang Riha, MD; Melchior Hohensinn, MD; Gerhard Nix, MD; Alois K. Dexl, MD, MSc; Günther Grabner, MD Submitted: 10/27/09; Accepted: 2/16/10; Posted: 4/15/10
In a series of 32 patients with the implantation of a small aperture AcuFocus intracorneal inlay in one eye for increased depth of field, at 2 years postoperatively, 95% of patients had J3 or better uncorrected near visual acuity (preop, 30%) and 70% had 20/25 or better intermediate uncorrected visual acuity (preop, 25%) with a statistically significant subjective improvement in near and intermediate tasks reported on a questionnaire. Uncorrected distance visual acuity was 20/20 or better in 75% of cases (preop 100%). [Get full text]
Intra- and Postoperative Variation in Ocular Response Analyzer Parameters in Keratoconic Eyes After Corneal Cross-linking
Paolo Vinciguerra, MD; Elena Albè, MD; Ashraf M. Mahmoud, PhD; Silvia Trazza, BS;
Farhad Hafezi, MD; Cynthia J. Roberts, PhD Submitted: 1/22/09; Accepted: 2/9/10; Posted: 4/15/10
In a series of 24 eyes with keratoconus treated by corneal collagen cross-linking (CXL) and measured by corneal topography and the Ocular Response Analyzer, both intraoperatively and postoperatively, and followed out to 1 year, there was no change in corneal hysteresis or corneal resistance factor indicating that the biomechanics of the cornea were altered minimally by CXL. However, there was increased regularity of the cornea and a decrease in a corneal steepening. [Get full text]
Clinical Outcomes of Complex and Uncomplicated Cataractous Eyes After
Lens Replacement With the AcrySof Toric IOL
Johnny L. Gayton, MD, FSEE; ReBecca A. Seabolt, COT, CCRC Submitted: 6/26/09; Accepted: 2/16/10; Posted: 4/1/10
In a series of 110 eyes with cataract extraction and pre-existing astigmatism in addition to other ocular complex problems, the use of the Alcon toric IOL in combination with other procedures reduced astigmatism. [Get full text]
Real Ray Tracing Simulation Versus Clinical Outcomes of Corneal Excimer Laser Surface Ablations
Jens Einighammer, PhD; Theo Oltrup, Dipl-Ing; Thomas Bende, PhD; Benedikt Jean, MD Submitted: 8/21/09; Accepted: 2/9/10; Posted: 4/1/10
In a series of 34 myopic eyes without astigmatism treated by surface ablation with the SCHWIND excimer laser system, the simulation of the Munnerlyn ablation profile showed neither an increase in oblateness of the cornea nor a big increase in higher order aberrations. In contrast, the corneas after real surgery showed increased oblateness and increased corneal higher order aberrations. These findings imply that wound healing and corneal biomechanics may play a role in clinical outcome. A literature review is presented. [Get full text]
Live or Let Die: Epithelial Flap Vitality
and Keratocyte Proliferation Following LASEK and Epi-LASIK in Human Donor and Porcine Eyes
Romesh I. Angunawela, MD, MRCOphth; Christoph Winkler von Mohrenfels, MD;
Anupma Kumar, MRCOphth; David P.S. O'Brart, MD, FRCOphth; John Marshall, PhD
Received: 7/7/09; Accepted: 2/4/10; Posted: 4/1/10
Laboratory studies indicate greater epithelial cell vitality and greater stromal keratocyte proliferation after an epithelial flap made with an epikeratome than after an epithelial flap created with alcohol assistance during surface excimer laser corneal ablation procedures. [Get full text]
LASIK Correction of Vision in Adults With Unilateral Amblyopia
Faik Oruçoglu (Orucov), MD; Joseph Frucht-Pery, MD; David Landau, MD; Eyal Strasman, MD; Abraham Solomon, MD Submitted: 7/31/09; Accepted: 2/2/10; Posted: 4/1/10
In a series of 30 patients with one amblyopic eye (CDVA 0.6, Snellen equivalent 20/30) and no amblyopia in the other eye, CDVA in the amblyopic eyes improved 2 or more lines in 5 (17%) eyes. [Get full text]
Topography-guided vs Wavefront-optimized Surface Ablation for Myopia Using the WaveLight Platform: A Contralateral Eye Study
Khalil Ghasemi Falavarjani, MD; Masih Hashemi, MD; Mehdi Modarres, MD;
Mostafa Soltan Sanjari, MD; Niloufar Darvish, BSc; Arzhang Gordiz, MD
Submitted: 5/11/09; Accepted: 2/9/10; Posted: 3/15/10
In a double-masked, randomized, prospective, contralateral study using the WaveLight platform with topography-guided treatment in one eye and wavefront-optimized treatment in the other eye with PRK for myopia in 20 patients, visual acuity and contrast sensitivity outcomes were essentially the same with both techniques. [Get full text]
Incidence of Nd:YAG Capsulotomy After Implantation of AcrySof Multifocal and Monofocal Intraocular Lenses: A Case Controlled Study
Vipul C. Shah, MD; Christopher Russo, MD; Richard Cannon, MD; Richard Davidson, MD;
Michael J. Taravella, MD Submitted: 7/25/09; Accepted: 2/2/10; Posted: 3/15/10
In a series of 257 eyes receiving an AcrySof monofocal lens and 142 eyes receiving an AcrySof RESTOR lens, 6% of eyes in the monofocal group compared to 16% of eyes in the multifocal group underwent Nd:YAG posterior capsulotomy, with no difference in the time after surgery between the two groups. [Get full text]
Topographic Stability After Hyperopic LASIK
Diego de Ortueta, MD; Samuel Arba Mosquera, MSc Submitted: 10/6/09; Accepted: 2/2/10; Posted: 3/1/10
In 66 consecutive eyes treated for hyperopic astigmatism with the SCHWIND ESIRIS excimer laser and followed for 36 months, there was stability of both topographic indices and manifest refraction. [Get full text] Optimized Zernike Term Selection in Customized Treatments for Laser Corneal Refractive Surgery: Case Report
Samuel Arba Mosquera, MSc; Diego de Ortueta, MD Submitted: 6/25/09; Accepted: 1/28/10; Posted: 3/1/10
By selecting certain Zernike terms deemed to be more visually important, and ignoring others, wavefront-guided aberrations can be used with removal of less corneal tissue. [Get full text]
LASIK for Myopic Astigmatism and Presbyopia Using Non-linear Aspheric Micro-monovision With the Carl Zeiss Meditec MEL 80 Platform
Dan Z. Reinstein, MD, MA(Cantab), FRCSC, FRCOphth; Timothy J. Archer, MA(Oxon), DipCompSci(Cantab); Marine Gobbe, PhD, MSTOptom Submitted: 12/30/08; Accepted: 12/1/09; Posted: 3/1/10
In a series of 272 myopic eyes with a spherical equivalent refraction ranging from -0.25 to -8.50 D, monovision was treated using the Zeiss MEL 80 platform with a target refraction of plano for the distance eye and -0.75 to -2.00 D for the near eye. Binocularly, 99% of patients achieved 20/20 or better and could read J5 at mean 1-year follow-up. [Get full text]
Implantation of a Complete Corneal Ring in an Intrastromal Pocket for Keratoconus
Haifa Mahmood, MD; R.S. Venkateswaran, OD; Albert Daxer, MD, PhD Submitted: 3/5/09; Accepted: 1/21/10; Posted: 2/15/10
In a series of six eyes with keratoconus, a complete 9-mm diameter corneal ring was implanted at 300-µm depth in a corneal pocket. Uncorrected distance visual acuity ranged from 20/125 to 20/400 preoperatively and from 20/35 to 20/100 postoperatively (six of seven eyes saw better than 20/60). [Get full text]
Conductive Keratoplasty to Treat Hyperopic Overcorrection After LASIK for Myopia
John S.M. Chang, MD; Silvania Y.F. Lau, BSc Submitted: 5/31/09; Accepted: 1/13/10; Posted: 2/15/10
In a series of seven eyes that were hyperopic after myopic LASIK, LightTouch conductive keratoplasty produced changes of -0.63 to -2.38 D, with early regression. [Get full text]
Transepithelial Corneal Collagen Cross-linking in Keratoconus
Antonio Leccisotti, MD, PhD; Tahmina Islam, FRCS, MRCOphth Submitted: 7/15/09; Accepted: 12/30/09; Posted: 2/15/10
Fifty-one patients with keratoconus underwent transepithelial corneal collagen cross-linking in the worse of two eyes. At 12 months after surgery, 1.00 to 1.50 D of central corneal flattening occurred with a wide range of results; progression of corneal steepness during that 1 year was less in the cross-linked eyes than in the control eyes. [Get full text]
Effect of Topical 0.5% Morphine on Postoperative Pain After Photorefractive Keratectomy
Ella G. Faktorovich, MD; Allan I. Basbaum, PhD, FRS Submitted: 5/19/09; Accepted: 12/29/09; Posted: 2/15/10
In a series of 40 patients, 0.5% morphine drops used every 2 hours for 1 day and every 4 hours for 2 additional days after PRK modestly reduced pain in 20 patients when compared to 20 controls without slowing epithelial healing. [Get full text]
Pentacam Characterization of Corneas With Fuchs Dystrophy Treated With Descemet Membrane Endothelial Keratoplasty
Robert O. Kwon, MD; Marianne O. Price, PhD; Francis W. Price, Jr, MD; Renato Ambrósio, Jr, MD; Michael W. Belin, MD Submitted: 10/7/09; Accepted: 12/9/09; Posted: 2/15/10
In a series of 29 eyes with Fuchs corneal dystrophy that received Descemet membrane endothelial keratoplasty (DMEK), the anterior corneal curvature measured by the Pentacam did not change from pre- to postoperative and was similar to normal corneal curvature. Corneal thickness decreased significant postoperatively. [Get full text]
Factors Related to the Correction of Astigmatism by LASIK After Penetrating Keratoplasty
Hyun Soo Lee, MD, PhD; Man Soo Kim, MD, PhD Submitted: 5/30/09; Accepted: 12/9/09; Posted 2/15/10
A series of 75 eyes with penetrating keratoplasty with all sutures removed received LASIK with the VISX S4 laser for the correction of 2.25 to 10.00 D of refractive astigmatism (mean 6.80 D), reducing the astigmatism to a range of 8.75 to 0.25 (mean 2.90 D); mean spherical equivalent refraction was decreased from 5.60 to 1.20 D. Vector analysis of the astigmatism is reported. [Get full text]
Decision Assistant Wizard to Standardize Optimal Outcomes in Excimer Laser Refractive Corneal Surgery
Maria Clara Arbelaez, MD; Tobias Ewering, OD; Samuel Arba Mosquera, MSc Submitted: 4/29/09; Accepted: 12/9/09; Posted: 2/15/10
A five-step decision tree can help guide surgeons in selecting the most appropriate use of excimer laser programs (eg, wavefront-guided or only spherocylindrical correction) for individual eyes. [Get full text]
Outcomes of Corneal Spherical Aberration-guided Cataract Surgery Measured by the OPD-Scan
Jonathan D. Solomon, MD Submitted: 6/2/09; Accepted: 11/11/09; Posted: 2/1/10
In a series of 40 consecutive eyes with cataract surgery using preoperative corneal spherical aberration as a guide, 3 intraocular lenses (Tecnis Z9003, Alcon AcrySof SN60WF, and Bausch & Lomb LI61AOV) were selected to create a postoperative total ocular spherical aberration near zero. Total postoperative ocular spherical aberration for the entire group measured 0.019 &mirco;m. [Get full text]
Distribution of Angle Kappa Measurements With Orbscan II in a Population-based Survey
Hassan Hashemi, MD; Mehdi KhabazKhoob, MSc; Kamran Yazdani, MD; Shiva Mehravaran, MD; Ebrahim Jafarzadehpur, PhD; Akbar Fotouhi, MD, PhD Submitted: 3/15/09; Accepted: 12/8/09; Posted: 1/15/10
In a population-based group of 800 eyes, the mean angle kappa was 5.46° (range: 2.0 to 9.0°; 95% confidence interval, 5.3 to 5.62). [Get full text]
Mechanism of Action of the Tetraflex Accommodative Intraocular Lens
James S. Wolffsohn, PhD; Leon N. Davies, PhD; Navneet Gupta, PhD; Shehzad A. Naroo, PhD; George A. Gibson, PhD; Toshifumi Mihashi, PhD; Sunil Shah, FRCS, FRCOphth Submitted: 6/20/09; Accepted: 12/1/09; Posted: 1/15/10
In 13 eyes that received the Tetraflex accommodating intraocular lens followed for at least 2 years, measurements indicate that the lens does not move in an anterior-posterior direction, but may undergo flexing changes that affect higher order aberrations, which might account for the improved near vision with the lens in some patients. [Get full text]
Intraoperative Complications of LASIK Flaps Using the IntraLase Femtosecond Laser in 3009 Cases
James A. Davison, MD, FACS; Steven C. Johnson, MD Submitted: 3/26/09; Accepted: 11/25/09; Posted: 1/15/10
In a consecutive series of 3009 LASIK operations using the IntraLase femtosecond laser to create the corneal flap, 0.37% of eyes had an intraoperative complication, most commonly a disruption of the suction ring adherence. [Get full text]
Optical and Topographic Changes in Keratoconus After Implantation of Ferrara Intracorneal Ring Segments
Islam Mahmoud Hamdi, FRCS(Glasg), PhD Submitted: 1/30.09; Accepted: 11/17/09; Posted: 1/15/10
In a series of 37 eyes with varying types of keratoconus, Ferrara Ring intracorneal ring segments were implanted, flattening the central cornea, improving the optical path difference refraction, decreasing the RMS for higher order aberrations, but no difference in the point spread function or modulation transfer function values. [Get full text]
Outcomes and Patient Satisfaction After Presbyopic Bilateral Lens Exchange With the ReSTOR IOL in Emmetropic Patients
José F. Alfonso, MD, PhD; Luís Fernández-Vega, MD, PhD; Beatriz Valcárcel, OD;
Teresa Ferrer-Blasco, PhD; Robert Montés-Micó, PhD
Submitted: 5/2/08; Accepted: 11/3/09; Posted: 1/15/10
In a series of 23 patients that underwent presbyopic lens exchange with bilateral AcrySof ReSTOR Natural IOL implantation, all eyes were within ±0.50 D of the desired refraction and all patients reported good quality of vision and satisfaction at distance and near 6 months postoperatively. [Get full text]
Corneal Ablation Depth Readout of the MEL 80 Excimer Laser Compared to Artemis Three-dimensional Very High-frequency Digital Ultrasound Stromal Measurements
Dan Z. Reinstein, MD, MA(Cantab), FRCSC, FRCOphth;
Timothy J. Archer, MA(Oxon), DipCompSci(Cantab); Marine Gobbe, MST(Optom), PhD
Submitted: 5/22/09; Accepted: 10/15/09; Posted: 1/15/10
In a series of 121 eyes, the depth of the stromal ablation as measured by the Zeiss MEL 80 excimer laser was approximately 20 µm greater than the readings obtained postoperatively of corneal thickness alone by the Artemis very high-frequency ultrasound. [Get full text]
Pupil Size, White-to-White Corneal Diameter, and Anterior Chamber Depth in Patients With Myopia
José F. Alfonso, MD, PhD; Teresa Ferrer-Blasco, PhD; José M. González-Méijome, PhD;
M. García-Manjarres, OD; Sofia C. Peixoto-de-Matos, OD; Robert Montés-Micó, PhD Submitted: 8/20/09; Accepted: 11/3/09; Posted: 12/15/09
In a series of 964 myopic eyes, the white-to-white diameter was constant at approximately 11.69 mm; anterior chamber depth averaged approximately 3.23 mm in the shallower and higher myopic eyes; average photopic pupil size was 4.90 mm; and average mesopic pupil size was 6.50 mm, decreasing with higher myopia. [Get full text]
Determining Spherocylindrical Correction Using Four Different Wavefront Error Analysis Methods: Comparison to Manifest Refraction
Charles E. Campbell, BS Submitted: 7/14/09; Accepted: 11/3/09; Posted: 12/15/09
In a series of 882 eyes measured before vision correction surgery with the VISX laser, smaller pupil methods measured the spherical component better whereas larger pupil measurements measured the astigmatic component better compared to manifest refraction. The spherical equivalent refraction was not optimally measured with any of the four approaches (standard deviation 0.94 D). A manifest refraction should be incorporated in preoperative wavefront-guided excimer laser corneal surgery planning. [Get full text]
US FDA Clinical Trial of the Tetraflex Potentially Accommodating IOL: Comparison to Concurrent Age-matched Monofocal Controls
Donald R. Sanders, MD, PhD; Monica L. Sanders, BS; Tetraflex Presbyopic IOL Study Group Submitted: 5/12/09; Accepted: 11/3/09; Posted: 12/15/09
In the US 12-center FDA clinical study, 255 patients received Tetraflex potentially accommodating IOLs bilaterally and 101 patients received 3-piece hydrophilic acrylic STAAR monofocal IOLs. Patients with the Tetraflex lens could read faster at smaller print sizes, wore reading glasses less frequently, and had better uncorrected distance visual acuity. [Get full text]
Traumatic Flap Striae 6 Years After LASIK: Case Report and Literature Review
Roxana Ursea, MD; Matthew T. Feng, MD Submitted: 5/1/09; Accepted: 11/3/09; Posted: 12/15/09
The authors present a case of ocular trauma 6 years after LASIK that resulted in a flap striae without flap dislocation as well as a literature review of striae and their management. [Get full text]
Quantitative Assessment of Bandage Soft Contact Lens Wear Immediately After LASIK
Faik Orucov, MD; Joseph Frucht-Pery, MD; Frederick D. Raiskup, MD; Eyal Strasman, MD; David Landau, MD; Abraham Solomon, MD
Submitted: 4/27/09; Accepted: 11/3/09; Posted: 12/15/09
In a series of 161 consecutive patients with bilateral simultaneous LASIK, soft contact lenses were applied immediately after surgery. Overnight wear was associated with more flap edema and mucoid secretion the next morning. The authors suggest applying a lens for 1 hour after surgery and then removing it. [Get full text]
Effects of Decentration of Photorefractive Keratectomy on the Induction of Higher Order Wavefront Aberrations
Sang-Bumm Lee, MD, PhD; Bo-Sung Hwang, MD; Jun-Yeop Lee, MD Submitted: 12/6/08; Accepted: 10/27/09; Posted: 12/15/09
In 95 eyes that received excimer laser PRK using a manually adjusted technique for the VISX S4 ActiveTrak system, increasing decentration produced increases in total higher order aberration, spherical aberration, and coma. A literature review of the change in higher order aberrations after refractive surgery is included. [Get full text]
Device for Improving Quantification of Reading Acuity and Reading Speed
Alois K. Dexl, MD, MSc; Horst Schlögel, PhD; Michael Wolfbauer; Günther Grabner, MD Submitted: 7/4/08; Accepted: 10/14/09; Posted: 12/1/09
A new device, the Salzburg Reading Desk, which uses the Radner reading charts and video-stereo-photometry to measure reading distance, allows automatic evaluation of reading acuity and reading speed at best reading distance under standardized conditions. Reading vision at best distance was found to be better than at fixed distance. [Get full text]
Sequential In Vivo Confocal Microscopy Study of Corneal Wound Healing After Cross-linking in Patients With Keratoconus
J. Oscar Croxatto, MD; Adriana E. Tytiun, MD; Carlos J. Argento, MD, PhD Submitted: 3/16/09; Accepted: 10/13/09; Posted: 11/16/09
Corneal cross-linking induces cellular wound healing and alters the normal structure and cellularity of the cornea for up to 3 years after treatment. [Get full text]
Intraoperative Videokeratography in Penetrating Keratoplasty and Excimer Laser-assisted Lamellar Keratoplasty for Keratoconus
Leopoldo Spadea, MD; Arianna Fiasca, MD; Simone Federici, MD Submitted: 12/17/08; Accepted: 10/13/09; Posted: 11/16/09
Videokeratography was used to adjust suture tension to minimize surgically induced astigmatism. Astigmatism decreased significantly in groups, and final astigmatism after 2 years was closely related to early postoperative values, indicating the benefit of intraoperative adjustments. [Get full text]
Biomechanical and Tomographic Analysis of Unilateral Keratoconus
Bruno M. Fontes, MD; Renato Ambrósio, Jr, MD, PhD; Marcella Salomão, MD; Guillermo C. Velarde, DSc; Walton Nosé, MD Submitted: 9/27/08; Accepted: 10/6/09; Posted: 11/16/09
Using the Ocular Response Analyzer to measure biomechanical properties of eyes with keratoconus, fellow eyes in the same patient, and control groups, the authors did not find statistically significant differences among these three groups, although the keratoconus in fellow eyes had numerically different values compared to normal control eyes. [Get full text]
Repeatability of Layered Corneal Pachymetry With the Artemis Very High-frequency Digital Ultrasound Arc-Scanner
Dan Z. Reinstein, MD, MA(Cantab), FRCSC, FRCOphth; Timothy J. Archer, MA(Oxon), DipCompSci(Cantab); Marine Gobbe, MST(Optom), PhD; Ronald H. Silverman, PhD; D. Jackson Coleman, MD Submitted: 12/30/08; Accepted: 9/29/09; Posted: 11/16/09
Using Artemis very high-frequency digital ultrasound, repeatability values for corneal epithelial thickness was 0.58 µm and for the stroma, cornea, LASIK flap, and residual stromal bed was approximately 1.7 &mirco;m. [Get full text]
Epithelial Thickness After Hyperopic LASIK: Three-dimensional Display With Artemis Very High-frequency Digital Ultrasound
Dan Z. Reinstein, MD, MA(Cantab), FRCSC, FRCOphth; Timothy J. Archer, MA(Oxon), DipCompSci(Cantab); Marine Gobbe, MST(Optom), PhD; Ronald H. Silverman, PhD; D. Jackson Coleman, MD Submitted: 5/22/09; Accepted 9/22/09; Posted: 11/16/09
Using high resolution ultrasound to measure corneal epithelial thickness in 65 eyes following LASIK for hyperopia showed a doughnut pattern, with thinner epithelium over the apex and thicker epithelium paracentrally at the 3.4-mm radius. [Get full text]
Pentacam Scheimpflug Evaluation of Corneal Volume After LASIK
Camila M. Gadelha P. Diniz, MD; Rossen M. Hazarbassanov, MD; Ester Yamazaki, MD; Celina Murata, MD; Felipe Mallmann, MD; Mauro Campos, MD Submitted: 1/6/09; Accepted: 9/3/09; Posted: 11/16/09
In a series of 49 eyes that underwent LASIK for myopia and were analyzed by the Pentacam Scheimpflug instrument, there was a good correlation between the spherical equivalent refraction treated and the laser ablation volume. [Get full text]
LASIK Outcomes Following Multifocal and Monofocal Intraocular Lens Implantation
David P. Piñero, PhD; María José Ayala Espinosa, MD, PhD; Jorge L. Alió, MD, PhD Submitted: 12/23/08; Accepted: 10/6/09; Posted: 11/2/09
LASIK treatment for residual refractive error after cataract surgery and intraocular lens implantation improved visual function. Outcomes were better for eyes with monofocal intraocular lenses than with multifocal intraocular lenses. Hyperopic eyes implanted with multifocal intraocular lenses had the poorest results. [Get full text]
Prospective Randomized Trial of Limbal Relaxing Incisions Combined With Microincision Cataract Surgery
Masayuki Ouchi, MD, PhD; Shigeru Kinoshita, MD, PhD Submitted: 2/6/09; Accepted: 8/13/09; Posted: 10/15/09
In a series of eyes that had cataracts removed using bimanual microincision cataract surgery technique, 96 eyes had limbal relaxing incisions for astigmatism and 93 had no relaxing incisions, with both groups having a mean preoperative cylinder of approximately 1.70 D. At 6 months postoperative, the mean astigmatism was 0.56 in the limbal relaxing incision group and 1.51 in the non-incision group. [Get full text]
Intraocular Straylight and Contrast Sensitivity After Contralateral Wavefront-guided LASIK and Wavefront-guided PRK for Myopia
Jackson Barreto, Jr, MD; Mirella T.S. Barboni, MSc; Claudia Feitosa-Santana, PhD; João R. Sato, MSc; Samir J. Bechara, MD; Dora F. Ventura, PhD; Milton Ruiz Alves, MD Submitted: 1/22/09; Accepted: 9/3/09; Posted: 10/1/09
In a prospective, randomized right/left eye contralateral study of 11 patients who received PRK in one eye and LASIK in the other eye using the wavefront-guided NIDEK EC-5000CXIII excimer laser with the OPDCAT platform, there was no difference between PRK and LASIK in terms of the amount of induced higher order aberrations, which increase was approximately 0.12 µm for total higher order aberrations. [Get full text]
Effect of Monochromatic Induced Aberrations on Visual Performance Measured by Adaptive Optics Technology
Hélène Rouger, MSc; Yohann Benard, MSc; Richard Legras, PhD
Submitted: 4/8/09; Accepted: 7/29/09; Posted: 9/1/09
In four patients, adaptive optics were used to induce lower and higher order optical aberrations, indicating that Zernike modes near the center and top of the Zernike pyramid decreased visual acuity more than those at the edge or the bottom of the pyramid. [Get full text]
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